Table 3. Summary of Studies Assessing Hepatic Steatosis Using B-Mode Ultrasound-Guided Attenuation Imaging.

Study	N	Technique	Reference Standard	r	Target Degree of Steatosis	Optimal Cutoff (dB/cm/MHz)	AUROC	Sen (%)	Spe (%)
Bae et al. [20]	108	ATI (Canon)	Biopsy	0.66	≥ S1 (5%)	0.64	0.84	75	77
					≥ 10%	0.66	0.88	80	83
					≥ S2	0.70	0.89	86	81
					≥ S3	0.75	0.93	100	82
Tada et al. [98]	148	ATI (Canon)	Biopsy	No data	≥ S1 (5%)	0.66	0.85	68	88
					≥ S2	0.67	0.91	92	84
					≥ S3	0.68	0.91	100	75
Jeon et al. [92]	87	ATI (Canon)	MRI-PDFF	0.66	≥ 5%	0.59	0.76	88	62
					≥ 10%	0.65	0.88	85	72
Dioguardi Burgio et al. [93]	101	ATI (Canon)	Biopsy	0.58	≥ S1 (5%)	0.69	0.81	76	86
					≥ S2	0.72	0.89	96	74
Jesper et al. [94]	27	ATI (Canon)	Biopsy	0.65	≥ S2	0.64	0.98	90	94
					≥ S3	0.68	0.98	100	90
Tada et al. [95]	119	ATI (Canon)	MRI-PDFF	0.70	≥ S1 (5.2%)	0.63	0.81	68	86
					≥ S2 (11.3%)	0.73	0.87	79	91
					≥ S3 (17.1%)	0.75	0.94	93	89
Ferraioli et al. [91]	72	ATI-Pen (Canon)	MRI-PDFF	0.78	≥ 5%	0.69	0.90	79	96
		ATI-Gen (Canon)	MRI-PDFF	0.83	≥ 5%	0.62	0.92	81	96
Fujiwara et al. [21]	163	UGAP (GE Healthcare)	Biopsy	0.78	≥ S1 (5%)	0.53	0.90	81	87
					≥ S2	0.60	0.95	86	82
					≥ S3	0.65	0.96	80	90
Tada et al. [96]	126	UGAP (GE Healthcare)	MRI-PDFF	0.75	≥ S1 (5.2%)	0.60	0.92	86	89
					≥ S2 (11.3%)	0.69	0.87	83	81
					≥ S3 (17.1%)	0.69	0.89	97	71
Tamaki et al. [22]	351	ATT (Hitachi)	Biopsy	0.47	≥ S1 (5%)	0.62	0.79	72	72
					≥ S2	0.67	0.87	82	82
					≥ S3	0.73	0.96	87	89
Jeon et al. [97]	120	TAI (Samsung)	MRI-PDFF	0.66	≥ 5%	0.88	0.86	78	79
					≥ 10%	0.98	0.84	64	93

AUROC = area under the receiver operating characteristic curve, PDFF = proton density fat fraction, r = correlation coefficient, Sen = sensitivity, Spe = specificity