Table 2.
Study design for interventional studies compared with COVID-19 and others
| Interventional Studies | COVID-19 (n=3622) | Others (n=37539) | P value |
|---|---|---|---|
| Allocation: N/A | 618(17.06%) | 9988(26.61%) | <0.001 |
| Intervention Model: Crossover Assignment | 0(0.00%) | 9(0.02%) | 0.582 |
| Intervention Model: Parallel Assignment | 0(0.00%) | 8(0.02%) | 0.619 |
| Intervention Model: Sequential Assignment | 10(0.28%) | 317(0.84%) | 0.030 |
| Intervention Model: Single Group Assignment | 608(16.79%) | 9654(25.72%) | 0.019 |
| Allocation: Non-Randomized | 330(9.11%) | 3545(9.44%) | 0.513 |
| Intervention Model: Crossover Assignment | 19(0.52%) | 157(0.42%) | 0.268 |
| Intervention Model: Factorial Assignment | 2(0.06%) | 41(0.11%) | 0.523 |
| Intervention Model: Parallel Assignment | 224(6.18%) | 2069(5.51%) | 0.001 |
| Intervention Model: Sequential Assignment | 53(1.46%) | 870(2.32%) | 0.001 |
| Intervention Model: Single Group Assignment | 32(0.88%) | 408(1.09%) | 0.321 |
| Allocation: Randomized | 2673(73.80%) | 23970(63.85%) | <0.001 |
| Intervention Model: Crossover Assignment | 87(2.40%) | 2494(6.64%) | <0.001 |
| Intervention Model: Factorial Assignment | 47(1.30%) | 388(1.03%) | 0.589 |
| Intervention Model: Parallel Assignment | 2381(65.74%) | 20106(53.56%) | <0.001 |
| Intervention Model: Sequential Assignment | 123(3.40%) | 656(1.75%) | <0.001 |
| Intervention Model: Single Group Assignment | 35(0.97%) | 326(0.87%) | 0.830 |
| Allocation: Unknown | 1 (0.03%) | 36(0.10%) | 0.151 |