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. 2022 Jan 10;116:210–215. doi: 10.1016/j.ijid.2022.01.015

Table 3.

Study design for observational studies compared with COVID-19 and others

Observational Studies COVID-19 (n=2786) Others (n=11387) Pvalue
Observational Model: Case-Control 312(10.85%) 1443(12.67%) 0.034
Time Perspective: Cross-Sectional 41(1.43%) 299(2.63%) 0.002
Time Perspective: Prospective 176(6.12%) 893(7.84%) 0.072
Time Perspective: Retrospective 82(2.85%) 206(1.81%) <0.001
Time Perspective: Other 13(0.45%) 45(0.40%) 0.348
Observational Model: Case-Crossover 29(1.01%) 106(0.93%) 0.592
Time Perspective: Cross-Sectional 11(0.38%) 38(0.33%) 0.836
Time Perspective: Prospective 11(0.38%) 59(0.52%) 0.090
Time Perspective: Retrospective 6(0.38%) 9(0.08%) 0.070
Time Perspective: Other 1(0.03%) 0(0.00%) 0.215
Observational Model: Case-Only 296(10.29%) 1406(12.35%) 0.012
Time Perspective: Cross-Sectional 41(1.43%) 225(1.98%) 0.354
Time Perspective: Prospective 156(5.42%) 881(7.74%) 0.001
Time Perspective: Retrospective 72(2.50%) 242(2.13%) 0.004
Time Perspective: Other 27(0.94%) 58(0.51%) <0.001
Observational Model: Cohort 1738(60.43%) 6937(60.92%) 0.155
Time Perspective: Cross-Sectional 143(4.97%) 497(4.36%) 0.129
Time Perspective: Prospective 1141(39.67%) 5155(45.27) <0.001
Time Perspective: Retrospective 342(11.89%) 1049(9.21%) <0.001
Time Perspective: Other 112(3.89%) 236(2.07%) <0.001
Observational Model: Ecologic or Community 95(3.30%) 139(1.22%) <0.001
Time Perspective: Cross-Sectional 37(1.29%) 73(0.64%) 0.041
Time Perspective: Prospective 45(1.56%) 48(0.42%) 0.049
Time Perspective: Retrospective 8(0.28%) 10(0.09%) 0.729
Time Perspective: Other 5(0.17%) 8(0.07%) 0.872
Observational Model: Family-Based 7(0.24%) 33(0.29%) 0.731
Time Perspective: Cross-Sectional 5(0.17%) 7(0.06%) 0.017
Time Perspective: Prospective 2(0.07%) 20(0.18%) 0.130
Time Perspective: Retrospective 0(0.00%) 2(0.02%) 0.677
Time Perspective: Other 0(0.00%) 4(0.04%) 0.448
Observational Model: Other 308(10.71%) 1319(11.58%) 0.433
Time Perspective: Cross-Sectional 80(2.78%) 286(2.51%) 0.104
Time Perspective: Prospective 137(4.76%) 716(6.29%) 0.002
Time Perspective: Retrospective 56(1.95%) 185(1.62%) 0.064
Time Perspective: Other 35(1.22%) 132(1.16%) 0.480
Observational Model: Unknown 1(0.03%) 4(0.04%) 0.665