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. 2022 Jan 5;15:45–58. doi: 10.2147/DMSO.S342799

Table 1.

Normalized Body Composition Data for Gpr75 KO Mice

Mice Age (Weeks) Genotype N Body Weight (g) Body Fat (g) % Body Fat LBM
All adult mice 11–24 WT 103 100 ± 11 100 ± 27 100 ± 19 100 ± 8
KO 118 83 ± 13*** 51 ± 21*** 61 ± 18*** 96 ± 10***
Adult male mice fed chow 14–24 WT 15 100 ± 9 100 ± 21 100 ± 17 100 ± 9
KO 13 98 ± 13 68 ± 22*** 69 ± 15*** 105 ± 9
Adult female mice fed chow 14–24 WT 16 100 ± 10 100 ± 25 100 ± 19 100 ± 8
KO 20 89 ± 11** 66 ± 21*** 74 ± 17*** 95 ± 10
Adult male mice fed HFD 11–24 WT 41 100 ± 12 100 ± 30 100 ± 21 100 ± 7
KO 51 79 ± 10*** 46 ± 18*** 58 ± 18*** 93 ± 9***
Adult female mice fed HFD 15–24 WT 31 100 ± 12 100 ± 29 100 ± 18 100 ± 7
KO 34 82 ± 12*** 47 ± 19*** 56 ± 17*** 99 ± 9
All mice at weaning 3 WT 79 100 ± 17 100 ± 25 100 ± 10 100 ± 16
KO 81 97 ± 12 92 ± 18* 95 ± 9** 98 ± 12
Male mice at weaning 3 WT 40 100 ± 23 100 ± 28 100 ± 9 100 ± 22
KO 43 96 ± 16 92 ± 20 97 ± 10 96 ± 15
Female mice at weaning 3 WT 39 100 ± 17 100 ± 28 100 ± 12 100 ± 16
KO 38 97 ± 14 90 ± 19 94 ± 9 99 ± 14

Notes: KO mice different from WT mice, *P < 0.05; **P < 0.01; ***P < 0.001; Statistical analysis by Mann–Whitney test.

Abbreviations: N, number of mice; g, grams; LBM, lean body mass; WT, wild type; KO, knockout; HFD, high fat diet.