Table 2.
Serum Chemistries of Gpr75 KO Mice and Their WT Littermates
| Analyte | Units | WT | KO |
|---|---|---|---|
| Sodium | mmol/L | 147 ± 2 | 146 ± 1 |
| Potassium | mmol/L | 4.2 ± 0.4 | 4.6 ± 0.4 |
| Chloride | mmol/L | 114 ± 2 | 112 ± 3 |
| BUN | mg/dL | 20 ± 3 | 23 ± 3 |
| Creatinine | mmol/dL | 0.1 ± 0.01 | 0.1 ± 0.02 |
| Glucose | mg/dL | 199 ± 13 | 198 ± 30 |
| Calcium | mg/dL | 9.9 ± 0.4 | 9.8 ± 0.4 |
| Phosphate | mg/dL | 5.3 ± 1.1 | 5.5 ± 0.8 |
| Albumin | g/dL | 3.5 ± 0.3 | 3.5 ± 0.2 |
| Total Cholesterol | mg/dL | 121 ± 19 | 127 ± 8 |
| Triglycerides | mg/dL | 122 ± 42 | 81 ± 13** |
| Total Bilirubin | mg/dL | 0.25 ± 0.04 | 0.24 ± 0.08 |
| Alkaline phosphatase | IU/L | 133 ± 55 | 97 ± 29 |
| ALT | IU/L | 40 ± 9 | 33 ± 8 |
Notes: For each KO line, blood was drawn on 8 fed KO mice (4 male, 4 female) and 4 fed WT mice (2 male, 2 female) at 15 weeks of age as described in Materials and Methods. The only comparison where KO and WT data differ is in bold font; **P < 0.01.
Abbreviations: WT, wild type; KO, knockout; mmol, millimole; L, liter; mg, milligram; dL, deciliter; g, gram; IU, international units; BUN, blood urea nitrogen; ALT, alanine aminotransferase.