Table 1. Study assessments in the ECOPD study.
Assessment | Visit 1 (baseline) | Visit 2 (12 months) | Visit 3 (24 months) | Visit 4 (36 months) |
---|---|---|---|---|
Anthropometric measurements | ||||
Height | √ | √ | √ | √ |
Weight | √ | √ | √ | √ |
Seated blood pressure | √ | √ | √ | √ |
Resting oxygen saturation | √ | √ | √ | √ |
Questionnaires | ||||
COPD epidemiological questionnaire | √ | √ | ||
Medical history | √ | √ | √ | √ |
Medications history | √ | √ | √ | √ |
mMRC dyspnea scale | √ | √ | √ | √ |
CAT | √ | √ | √ | √ |
CCQ | √ | √ | √ | √ |
Acute respiratory event/exacerbation assessment | √ | √ | √ | √ |
Pulmonary function | ||||
Pre-bronchodilator spirometry | √ | √ | √ | √ |
Post-bronchodilator spirometry | √ | √ | √ | √ |
Impulse oscillometry | √ | √ | √ | √ |
Chest CT | ||||
Inspiration | √ | |||
Expiration | √ | |||
Biomarkers | ||||
Blood samples | √ | √ | ||
Urine samples | √ | √ | ||
Induced sputuma | √ | √ | ||
Pollutant exposure measures | ||||
Satellite remote sensing/district and county based sampling | Daily monitoring | |||
Home monitoring/personal samplinga | √ | √ | √ | √ |
Exercise capacity | ||||
6MWTa | √ | √ | ||
CPETa | √ | √ |
a, subgroup A: completed by some participants. ECOPD study, Early Chronic Obstructive Pulmonary Disease study; COPD, chronic obstructive pulmonary disease; mMRC, modified British Medical Research Council; CAT, chronic obstructive pulmonary disease assessment test; CCQ, chronic obstructive pulmonary disease clinical questionnaire; CT, computed tomography; 6MWT, 6-minute walk test; CPET, cardiopulmonary exercise testing.