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. 2021 Dec;13(12):6855–6865. doi: 10.21037/jtd-21-1312

Table 3. Management of participants and lung cancer diagnosis after the first LDCT scan at baseline screening round according to NCCN and EUPS protocols.

Management NCCN protocol EUPS diameter protocol EUPS volume protocol
All participants (n=1,000)
   Next screening 949 (94.9%) 889 (88.9%) 936 (93.6%)
   Short-term repeat (3/6 months) 45 (4.5%) 97 (9.7%) 45 (4.5%)
   Referral to a pulmonologist 6 (0.6%) 14 (1.4%) 19 (1.9%)
Participants with solid nodule (n=103)
   Next screening 57 (55.3%) 13 (12.6%) 45 (43.7%)
   Short-term repeat (3/6 months) 42 (40.8%) 76 (73.8%) 43 (41.7%)
   Referral to a pulmonologist 4 (3.8%) 14 (13.6%) 15 (14.6%)
Participants with part-solid nodule (n=5)
   Next screening 0 0 0
   Short-term repeat (3/6 months) 3 5 1
   Referral to a pulmonologist 2 0 4
Participants with non-solid nodule (n=16)
   Next screening 16 0 15
   Short-term repeat (3/6 months) 0 16 1
   Referral to a pulmonologist 0 0 0
Participants without nodules (n=876)
   Next screening 876 876 876
   No. of lung cancer diagnosis until (including) second round 10 10 10

LDCT, low-dose computed tomography; NCCN, National Comprehensive Cancer Network; EUPS, European Position Statement.