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. 2022 Jan 10;23:15. doi: 10.1186/s13059-021-02589-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Highlighted conditions that modulate ACE2 expression. A,B Plots showing data from a study with GEO accession GSE89714. A A scatter plot showing the association between ACE2 expression and the embedded metadata. All metadata fields are concatenated for embedding. The plot only shows the sample title as labels. The labels are jittered to avoid perfect overlap. The color code represents the ACE2 expression level. B Box plot showing the ACE2 expression in normal hearts and hearts with hypertrophic cardiomyopathy. C,D Plots visualizing data from a study with GEO accession GSE104177, showing the ACE2 expression in breast cancer xenografts with or without RAD140 treatment. E,F Plots visualizing data from a study with GEO accession GSE114013, showing the ACE2 expression in two prostate cancer cell lines with or without itraconazole treatment