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. 2021 Dec;10(12):4526–4537. doi: 10.21037/tlcr-21-937

Table 4. Risk factors associated with postoperative complications after carinal resection and reconstruction with complete pulmonary parenchyma preservation.

Factors Univariate analysis Multivariate analysis
OR (95% CI) P OR (95% CI) P
Sex
   Male 0.833 (0.218–3.190) 0.790
   Female REF
Age 0.997 (0.952–1.044) 0.893
BMI
   Underweight 0.917 (0.051–16.494) 0.953 0.368 (0.016–8.277) 0.529
   Overweight 0.092 (0.010–0.838) 0.034 0.092 (0.009–0.922) 0.042
   Normal weight REF REF
Smoking history 0.477 (0.102–2.235) 0.348
Comorbidity 0.938 (0.211–4.166) 0.932
   Hypertension 0.567 (0.094–3.423) 0.536
   Diabetes NA > 0.99
   Coronary heart disease NA > 0.99
   Cerebral infarction NA > 0.99
   Deep vein thrombosis NA > 0.99
Previous lung surgery 0.487 (0.046–5.215) 0.552
Obstructive pneumonia or atelectasis 0.750 (0.118–4.760) 0.760
Preoperative endoscopic treatment NA > 0.99
Approach
   Posterolateral thoracotomy 1.300 (0.107–15.836) 0.837
   Other approaches REF
Ventilation strategy
   Crossfield intubation 1.056 (0.153–7.270) 0.956
   HFJV or ECMO REF
Release of hilar or ligament 0.205 (0.022–1.927) 0.209
Anastomosis wrapped 0.750 (0.118–4.760) 0.760
Type of reconstruction
   Double-barrel reconstruction/first type of Eschapasse reconstruction REF
   Second type of Eschapasse reconstruction/Barclay reconstruction 1.167 (0.269–5.054) 0.837
Blood loss (mL) 0.994 (0.987–1.002) 0.123 0.996 (0.988–1.003) 0.267
Operation duration (min) 0.995 (0.983–1.007) 0.427
The length of resected airway 0.978 (0.561–1.706) 0.938
Margins
   Positive 3.333 (0.717–15.506) 0.125 3.090 (0.533–17.899) 0.208
   Negative REF REF

BMI, body mass index; CI, confidence interval; HFJV, high-frequency jet ventilation; ECMO, extracorporeal membrane oxygenation; NA, not available; OR, odds ratio; REF, reference.