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. 2021 Dec;10(12):4368–4379. doi: 10.21037/tlcr-21-682

Table 2. Disease characteristics at the time of oligoprogression.

Variable N (%)
Type of immunotherapy (CPI Strategy)
   Monotherapy 4 (16.7)
   Combination 20 (83.3)
Lines of immunotherapy before oligoprogression
   1 16 (66.7)
   2 5 (20.8)
   3 3 (12.5)
Response to immunotherapy before oligoprogression
   CR 6 (25.0)
   PR 18 (75.0)
No. of oligoprogression
   1 14 (58.3)
   2 10 (41.7)
Site of oligoprogression
   Brain 14 (41.2)
   Lung 10 (29.4)
   Lymph node 5 (14.8)
   Adrenal gland 3 (8.8)
   Liver 1 (2.9)
   Cervical vertebra 1 (2.9)
Pattern of oligoprogression
   New metastasis 16 (47.1)
   Existing metastasis 18 (52.9)
Type of immunotherapy after oligoprogression (CPI Strategy-PO)
   Monotherapy 7 (29.2)
   Combination 17 (70.8)
Change of CPI Strategy
   Consistent Strategy (continue previous treatment or maintenance strategy) 17 (70.8)
   Monotherapy to combination 3 (8.8)
   Adjusted combination 4 (16.7)

Values presented are n (%) unless otherwise noted. CPI, checkpoint inhibitor; CR, complete response; PR, partial response; CPI Strategy-PO, strategy of checkpoint inhibitor post oligoprogression.