Table 1. The basic characteristics and their individual F statistics for selected summary level GWASs applied in our MR study.

Trait	Sample size	Sex	First author/consortium	F statistics
Overall C-reactive protein (CRP)	310,305	Males and females	–	3,135.39
East Asian-specific CRP variants	75,391	Males and females	Ishigaki K	762.53
Hispanic/Latin American-specific CRP variants	15,912	Males and females	Wojcik GL	161.73
European-specific CRP variants	204,402	Males and females	Neale lab	2,065.67
African American/Afro-Caribbean-specific CRP variants	6,203	Males and females	Pan-UKB team	63.66
South Asian-specific CRP variants	8,397	Males and females	Pan-UKB team	85.82
Lung cancer	27,209	Males and females	ILCCO	275.84
Lung adenocarcinoma	18,336	Males and females	ILCCO	186.21
Squamous cell lung cancer	18,313	Males and females	ILCCO	185.98

ILCCO, the International Lung Cancer Consortium.