Table 1.

The number of isolates for drug-resistance prediction concordant/disagreement with the phenotypic DST for the drugs present in the drug panels of both tools

Table 1a: The number of isolates (%) for drug-resistance prediction concordant/disagreement with the phenotypic DST for the first-line drugs.
	Rifampicin			Isoniazid			Pyrazinamide			Ethambutol
	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*
TBProfiler Short-read	23/24 (96.0)	1/24 (4.0)	na	24/24 (100.0)	0	na	21/24(87.5)	3/24(12.5)	na	16/24 (67.0)	8/24(33.0)	na
TBProfiler Long-read	22/24 (92.0)	2/24 (8.0)	na	24/24 (100.0)	0	na	19/24 (79)	5/24(21.0)	na	16/24 (67.0)	8/24(33.0)	na
Mykrobe Short-read	24/24 (100.0)	0	0	24/24 (100.0)	0	0	20/22 (91)	2/22(9.0)	2	19/24 (79.0)	5/24(21.0)	0
Mykrobe Long-read	21/21 (100.0)	0	3	15/17 (88.0)	2/17(12.0)	7	10/11 (91)	1/11(9.0)	13	19/23 (83.0)	4/23(17.0)	1
Table 1b: The number of isolates (%) for drug-resistance prediction concordant/disagreement with the phenotypic DST for the second-line drugs.
	Streptomycin			Fluoroquinolones			Amikacin			Capreomycin
	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*	Concor. (%)	Disagre. (%)	Other*
TBProfiler Short-read	14/15 (93.0)	1/15 (7.0)	na	15/15 (100.0)	0	na	15/15 (100.0)	0	na	15/15 (100.0)	0	na
TBProfiler Long-read	14/15 (93.0)	1/15(7.0)	na	15/15 (100.0)	0	na	15/15 (100.0)	0	na	15/15 (100.0)	0	na
Mykrobe Short-read	15/15 (100.0)	0	0	15/15 (100.0)	0	0	15/15 (100.0)	0	0	15/15 (100.0)	0	0
Mykrobe Long-read	15/15 (100.0)	0	0	15/15 (100.0)	0	0	15/15 (100.0)	0	0	15/15 (100.0)	0	0

∗Minor allele calls made for drug resistance in phenotypically susceptible or resistant isolates

Concor, Concordance; Disagre, Disagreement; na, Not applicable.