The distribution of antimicrobial resistance elements within the
K. pneumoniae
isolates from QECH. The phylogeny is based on a core genome SNP alignment of the Malawian isolates (n=86), and the branches are labelled with the ST. The panel adjoining the phylogeny shows the antimicrobial resistance phenotype and the absence/presence of key antimicrobial resistance genes and plasmids amongst the isolates. Beta-lactamase genes: bla
CTXM, bla
TEM, bla
OXA, bla
SHV. Quinolone resistance genes: aac3, aac6. Streptomycin resistance gene: strAB. Sulphonamide resistance gene: sul1. Chloramphenicol resistance genes: cat1, cat2. Tetracycline resistance gene: tetA. Aminoglycoside resistance genes: aadA, aad1. Trimethoprim resistance genes: dfrA1, dfrA2, dfrA14. Macrolide resistance gene: mph.