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. 2021 Nov 18;7(11):000696. doi: 10.1099/mgen.0.000696

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© 2021 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License.

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Fig. 2. — Summary of antimicrobial resistance genotype of C. difficile . (a) For evolutionary context, a neighbour-joining phylogeny based on MLST shows the global population structure of C. difficile . (b) The prevalence of C. difficile strains harbouring accessory AMR genes across different clades (leftmost) and the prevalence of resistance to important antimicrobial classes conferred mainly by accessory AMR genes. The presence of an aminoglycoside resistance gene (**) does not contribute to the definition of MDR C. difficile . (c) The prevalence of C. difficile strains having significant amino acid substitutions associated with AMR across different clades (leftmost) and the prevalence of resistance to important antimicrobial classes conferred mainly by amino acid substitution.