TABLE 2.
Regrouping factors | Group | Sample size | HR (95% CI) | Kaplan‐Meier p‐value | AUC | 95% CI |
---|---|---|---|---|---|---|
Gender | Male | 285 | 2.832 (2.22–3.60) | 2.85E‐10 | 0.925 | 0.88–0.87 |
Female | 229 | 2.238 (1.75–2.86) | 2.00E‐05 | 0.902 | 0.74–0.97 | |
Age at diagnosis | <45 | 302 | 2.145 (1.66–2.78) | 5.70E‐05 | 0.914 | 0.85–0.96 |
≥45 | 212 | 2.538 (1.99–3.24) | 1.11E‐08 | 0.895 | 0.83–0.96 | |
WHO grade | G2 | 248 | 2.263 (1.52–3.37) | 4.30E‐05 | 0.878 | 0.79–0.97 |
G3 | 265 | 2.122 (1.76–2.56) | 2.28E‐07 | 0.912 | 0.86–0.96 | |
Histologic subtype | Astrocytoma | 194 | 2.587 (1.97–3.40) | 6.08E‐07 | 0.954 | 0.91–0.99 |
Oligodendroglioma | 189 | 2.169 (1.54–3.05) | 4.33E‐04 | 0.841 | 0.75–0.93 | |
Mixed glioma | 131 | 2.366 (1.77–3.16) | 2.84E‐04 | 0.936 | 0.86–1.00 | |
IDH1 mutation | Yes | 91 | 1.919 (1.13–3.25) | 1.03E‐02 | 0.933 | 0.81–1.00 |
No | 34 | 3.258 (1.48–7.15) | 8.46E‐03 | 1.00 | 1.00–1.00 | |
Radiation therapy | Yes | 277 | 2.081 (1.71–2.54) | 7.31E‐09 | 0.915 | 0.87–0.96 |
No | 169 | 3.414 (2.72–5.36) | 8.00E‐03 | 0.879 | 0.77–0.97 | |
Family history of cancer | Yes | 132 | 2.909 (2.01–4.21) | 7.50E‐05 | 0.976 | 0.94–1.00 |
No | 210 | 2.379 (1.81–3.12) | 1.50E‐05 | 0.903 | 0.84–0.97 |