Fig. 3.

Date are presented as means ± SEM at each time point for the Zephyr valve group (■) and SoC group (o). The difference between group means is represented by (∆). Within each variable, data for the same subjects are reported at each time point; this represents the completed cases at 6 months for each measure with imputations at 3 months for any subject with a missing value. Imputations were performed using the “Last Observation Carried Forward” method. p values for FEV₁, SGRQ, 6MWD, and RV from the Student's t test, and for mMRC and the BODE index from the Wilcoxon test. SoC, standard of care; RV, residual volume; 6MWD, six-minute walk distance; SGRQ, St. George's Respiratory Questionnaire; mMRC, modified Medical Research Council.