Figure 1.
Swimmer’s plot summarizing clinical course with CRS, peak ICANS, and corresponding treatment for each patient. CRS was graded according to autologous stem cell transplantation consensus grading 2020. ICANS was graded retrospectively based on clinical notes from the patient information system. Corticosteroid application is indicated in milligram in gray graduated boxes. Time period represents hospitalization days starting at CART infusion. The graph is subdivided into axicabtagene ciloleucel (Yescarta) and tisagenlecleucel (Kymriah). * indicates deceased; X indicates application of tocilizumab; star indicates application of anakinra. CRS, cytokine release syndrome; ICANS, immune effector cell-associated neurotoxicity syndrome.