Table 2.
Trimester | Half-life (days) | Apparent clearance (L/hour) | Apparent volume of distribution (L) |
First | 21.4 (16.1) | 42.1 (15.3) | 27 589 (17 248) |
Second | 24.1 (16.7) | 48.8 (17.6) | 35 935 (19 645) |
Third | 22.1 (12.7) | 53.0 (18.9) | 36 201 (15 627) |
Post partum | 32.4 (20.2) | 33.2 (11.8) | 33 164 (16 478) |
*Data presented as mean (SD) of the empirical Bayesian estimates.
HCQ, hydroxychloroquine.