Genome organization of begomoviruses. The ORFs ([A]V1, [A]V2, [A]C1, [A]C2, [A]C3, [A]C4, BV1 and BC1) and their protein products (CP, capsid protein; MP, movement protein; Rep, replication-associated protein; TrAP, transcriptional activator protein; REn, replication enhancer protein; C4, C4 protein; NSP, nuclear shuttle protein) are shown. ORF [A]V2 is not present in New World begomoviruses. IR, intergenic region; LIR, long intergenic region; SIR, short intergenic region; CR, common region. The hairpin which includes the origin of replication is indicated in the IR/LIR.