Table 1.
Patients' characteristics, respiratory, hemodynamic, laboratory and microcirculatory parameters. MAP = Mean arterial pressure; WBC=White Blood Cells; RBC = Red Blood Cells; CRP=C-Reactive Protein; PT = prothrombin time ratio, LDH = lactose dehydrogenase; TVD = total small vessel density; PVD = Perfused Vessels Density; PPV = Proportion of Perfused Vessels; HI = heterogeneity index.
| Patient's characteristics | Case 1 | Case 2 | Case 3 |
|---|---|---|---|
| Age | 14 ys | 1 years 6 month | 15 days |
| Weight | 47 | 9,5 | 3,4 |
| Comorbidity | Lymphoma | Cystic fibrosis | |
| Ventilation setting | |||
| PIP | 32 | 20 | 18 |
| Peep | 15 | 7 | 6 |
| PaO2/FiO2 | 96 | 220 | 250 |
| FiO2 (%) | 80 | 40 | 35 |
| ECMO VA setting | |||
| LPM (l/min) | 0.58 | ||
| RPM | 3250 | ||
| FiO2 (%) | 75% | ||
| Hemodynamic variables | |||
| MAP (mmHg) | 70 | 85 | 65 |
| Noradrenaline (μg/kg/min) | 0.03 | 0.04 | – |
| Lactate (mmol/L) | 1.5 | 0.6 | 1.3 |
| Laboratory parameters | |||
| WBC (103/μL) | 0.26 | 25.24 | 5.56 |
| RBC (106/μL) | 3.54 | 3.61 | 4.08 |
| Platelets (103/μL) | 26.000 | 139.000 | 183.000 |
| Hemoglobin (gr/dL) | |||
| Ferritin (ng/mL) | 4879 | 501 | 531 |
| CRP (mg/dL) | 10.5 | 1.55 | 0.36 |
| D-dimer (μg/mL) | 2.65 | 1.46 | 2.45 |
| PT-ratio (%) | 1.34 | 1.89 | 1.09 |
| LDH (U/L) | 239 | 339 | 285 |
| Microcirculation parameters | |||
| TVD (mm/mm2) | 18.5 | 16.36 | 12.7 |
| PVD (mm/mm2) | 9.31 | 14.9 | 12.4 |
| PPV (%) | 79.3 | 89.7 | 98.7 |
| MFI (AU) | 1.3 | 2.6 | 2.6 |
| HI | 2.25 | 0.28 | 0.18 |
| Outcome | |||
| Survival PICU discharge | No | Yes | Yes |
| Survival at 28 days | No | Yes | Yes |