Table 1.

Clinical characteristics and results of RNA sequencing analysis for the two cases presented in this study

Case	Sex	Age at diagnosis	Cancer history	Colorectal polyps	Family history	MUTYH NM_001128425.1 variants identified	Zygosity	Results of RNA analysis	Other variants identified
1	F	Early 30s	Colon cancer	No report of polyps	Pancreatic, head and neck, gastric, and breast cancers	c.934-2A > G	Heterozygous	r.934_942del9 (in-frame deletion of 9 nt in exon 11)	None
2	F	No data	No personal history of cancer	7–8 polyps	Breast, pancreatic, prostate cancers, and lymphoma; possible colon and stomach cancers	c.934-2A > G	Heterozygous	r.934_942del9 (in-frame deletion of 9 nt in exon 11)	VUS in RAD50

(VUS) Variant of uncertain significance.