Table 1.
Total and differential cell counts of BAL fluid of vehicle or MWCNT instilled animals.
| Strain/Treatment | Total Cell Count (×106) | Macrophages (%) | Lymphocytes (%) | PMN (%) |
|---|---|---|---|---|
| C57BL/6 | ||||
| SHAM (N = 10) | 0.8 ± 0.1 | 98.1 ± 0.8 | 1.4 ± 0.6 | 0.5 ± 0.3 |
| MWCNT (N = 11) | 0.7 ± 0.1 | 95.6 ± 1.1 | 3.1 ± 0.8 | 1.3 ± 0.5 |
| ABCG1 KO | ||||
| SHAM (N = 16) | 2.0 ± 0.2 * | 90.1 ± 2.1 * | 5.3 ± 0.9 * | 4.7 ± 1.4 * |
| MWCNT (N = 12) | 2.2 ± 0.2 * | 85.1 ± 3.7 * | 7.7 ± 2.0 * | 7.3 ± 2.4 * |
* p ≤ 0.05 compared to C57BL/6J same treatment. Non-significant difference was observed between sham and MWCNT-instilled mice in the same genotype.