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Isolation and culture of circulating BMMPs. Freshly isolated Buffy-coat (A), adherent BMMPs showed their characteristics to form colonies (B), and their spindle-shape figure (C). Photos refer to day 0 (A) and to day 4 (B) and day 15 (C) of the primary culture. Scale bar = 50 μm (A–C). BMMPs showed an ability to differentiate into adipocytes (Di,ii), osteocytes (Ei,ii), and chondrocytes (Fi,ii). Scale bar= 100 μm (DiEiFi); Scale bar = 50 μm (Dii,Eii,Fii).
