Skip to main content
. 2021 Dec 22;23(1):78. doi: 10.3390/ijms23010078

Figure 8.

Figure 8

(A) Experimental wound model. Schematic representation of the nine experimental conditions: unscratched skin (control, TNFα, and HGF supplemented), scratched skin (scratched, TNFα, and HGF supplemented), and scratched skin and BMMPs infused (scratched, TNFα, and HGF supplemented, followed by BMMPs infusion). The scheme also shows the three time points taken into consideration (days one, three, and five after wound infliction). qPCR and ELISA were performed to measure expression levels of IL-8 and CD73 and protein levels of IL-8, SCF, and FGF-1, respectively (B). Schematic representation of the different experimental conditions on skin models on day three after wound infliction (C). The schemes show the effect of TNFα (A) and HGF (B) supplementation and BMMPs infusion with and in absence of damage. Evaluation of their effects was conducted at molecular level, by gene expression level quantification of IL-8 and CD73, and at protein level measurement of IL-8 and SCF. Created with BioRender.com. https://biorender.com/ (Accessed on 15 November 2021).