Table 1.
Table shows patient characteristics of the ACM and PLN cohort. Data depicted as average ±standard error of the mean. PKP2; plakophilin 2, DSP; desmoplakin, PLN; phospholamban, TFC Task Force Criteria 2010, ACM; arrhythmogenic cardiomyopathy, DCM; dilated cardiomyopathy. Students t-test when appropriate, *** p < 0.001, ** p < 0.01.
| Controls | ACM | PLN | |
|---|---|---|---|
| General | |||
| n | 34 | 33 | 17 |
| A verage age | 38.76 (±2.65) | 49.73 (±2.48) ** | 54.29 (±3.21) *** |
| M ale | 14 (41) | 19 (58) | 6 (35) |
| Pathogenic variant | |||
| PKP2 | - | 28 (85) | - |
| DSP | - | 2 (6) | - |
| P lakoglobin | - | 1 (3) | - |
| PLN | - | - | 17 (100) |
| N o known pathogenic variant | - | 2 (6) | - |
| TFC | |||
| Average | - | 4.70 (±0.43) | 1.75 (±0.60) |
| ACM (TFC ≥ 4) | - | 19 (58) | 3 (18) |
| DCM | - | - | 7 (41) |
| P reclinical variant carrier | - | 14 (42) | 7 (41) |