Table 3.
Patient outcomes before and after prolonged exposure to extreme cold.
| Analyzed Parameter (Unit of Measure) |
Results before Exposure to Extreme Cold | Results after Exposure to Extreme Cold | Change Compared to the Result before (% of Change) | Standard |
|---|---|---|---|---|
| RBC [×10^12/L] | 4.74 | 4.55 | −4.01 | 4.6–6.2 |
| HGB [g/dL] | 14.4 | 13.9 | −3.47 | 14–18 |
| HCT [%] | 44.1 | 42.6 | −3.40 | 42–52 |
| MCV [fl] | 93.1 | 93.7 | 0.64 | 82–94 |
| MCH [pg] | 30.5 | 30.6 | 0.33 | 27–32 |
| MCHC [g/dL] | 32.7 | 32.7 | no change | 30–38 |
| CHCM [g/dL] | 33.3 | 32.6 | −2.10 | 31–37 |
| RDW [%] | 13 | 12.4 | −4.62 | 11.5–14.5 |
| HDW [g/dL] | 2.48 | 2.51 | 1.21 | 2.2–3.2 |
| WBC [×10^9/L] | 4.18 | 3.28 | −21.53 | 4–10 |
| Neutrocytes [×10^9/L] | 2.08 | 1.72 | −17.31 | 2.2–7.0 |
| Eosinocytes [×10^9/L] | 0.19 | 0.1 | −47.37 | 0.0–0.5 |
| Basophils [×10^9/L] | 0.05 | 0.04 | −20.00 | 0.0–0.1 |
| Lymphocytes [×10^9/L] | 1.49 | 1.09 | −26.85 | 1.0–3.5 |
| Monocytes [×10^9/L] | 0.29 | 0.27 | −6.90 | 0.0–0.9 |
| PLT [×10^9/L] | 200 | 185 | −7.50 | 150–400 |
| MPV [fl] | 10.3 | 9.6 | −6.80 | 7.2–11.1 |
| PCT [%] | 0.21 | 0.18 | −14.29 | 0.120–0.380 |
| PDW [%] | 65.9 | 69.4 | 5.31 | 28.0–60.0 |
| Coagulology | ||||
| Prothrombin activity [%] | 92.17 | 110 | 19.34 | 80–130 |
| INR | 1.04 | 0.9 | −13.46 | 0.85–1.15 |
| aPTT [s] | 25.7 | 26.9 | 4.67 | 20.0–36.0 |
| Fibrinogen [g/L] | 2.13 | 2.65 | 24.41 | 1.8–3.5 |
| D-dimer [mg/L] | 0.17 | 0.102 | −40.00 | <0.5 |
| Biochemistry | ||||
| Iron [umol/L] | 23.3 | 17.2 | −26.18 | 14.0–32.0 |
| B12 [pg/mL] | 406 | 365 | −10.10 | 200–900 |
| Total bilirubin [umol/L] | 9.4 | 5.6 | −40.43 | 2.0–21.0 |
| ALP [U/L] | 44.4 | 56.1 | 26.35 | |
| AspAT [U/L] | 26.7 | 40.8 | 52.81 | 5–38 |
| AlAT [U/L] | 30.4 | 51.3 | 68.75 | 5–41 |
| GGT [U/L] | 13 | 12 | −7.69 | 5–55 |
| LDH [U/L] | 179.6 | 171.3 | −4.62 | 100–225 |
| Total protein [g/L] | 76.8 | 71.4 | −7.03 | 64–83 |
| Albumin [g/L] | 48.2 | 44.2 | −8.30 | 38.0–49.0 |
| Alpha-1-globulins [g/L] | 2.4 | 2.6 | 8.33 | 2.4–4.0 |
| Alpha-2-globulins [g/L] | 5.3 | 5.7 | 7.55 | 4.8–9.0 |
| Beta-1-globulins [g/L] | 5 | 4.8 | −4.00 | 3.2–6.3 |
| Beta-2-globulins [g/L] | 3.8 | 3.4 | −10.53 | 2.2–5.2 |
| Gamma globulins [g/L] | 12.2 | 10.7 | −12.30 | 6.8–15.0 |
| AG index | 1.68 | 1.62 | −3.57 | |
| IgG [g/L] | 12.2 | 11.3 | −7.38 | 6.9–14.0 |
| IgA [g/L] | 3.2 | 2.9 | −9.38 | 0.9–4.1 |
| IgM [g/L] | 1.5 | 1.2 | −20.00 | 0.3–2.1 |
| CRP [mg/L] | 0.21 | 0.26 | 23.81 | <5.0 |
| Prealbumins [g/L] | 0.377 | 0.319 | −15.38 | 0.210–0.410 |
| CK [U/L] | 239.3 | 259.9 | 8.61 | 24–198 |
| CK-MB [U/L] | 12.9 | 13.3 | 3.10 | 4–24 |
| Total cholesterol [mmol/L] | 6.29 | 5.92 | −5.88 | 3.0–5.0 |
| HDL [mmol/L] | 1.1 | 1.41 | 28.18 | >1.0 |
| LDL [mmol/L] | 4.9 | 4.31 | −12.04 | <3.0 |
| TG [mmol/L] | 1.82 | 1.46 | −19.78 | <1.7 |
| Alpha-amylase [U/L] | 30.7 | 30.3 | −1.30 | 28–100 |
| Lipase [U/L] | 25 | 30.8 | 23.20 | 13–60 |
| Glucose [mmol/L] | 5.89 | 5.21 | −11.54 | 3.9–5.5 |
| HBA1C [%] | 5.2 | 4.7 | −9.62 | 4.0–6.5 |
| Immunochemistry | ||||
| Testosterone [nmol/L] | 23.33 | 37.36 | 60.14 | 4.94–32.01 |
| NTproBNP [pg/mL] | 33.5 | 22.5 | −32.84 | ≤125 |
| Troponin I [pg/mL] | 10 | 10 | no change | 0.26.2 |
| TSH [microIU/mL] | 0.72 | 0.78 | 8.33 | 0.35–4.94 |
| FT3 [pmol/L] | 5.76 | 5.31 | −7.81 | 2.63–5.70 |
| FT4 [pmol/L] | 15.58 | 11.44 | −26.57 | 9.0–19.0 |
| IL6 [pg/mL] | 1.5 | 2.4 | 60.00 | ≤7.0 |
Abbreviations: RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; CHCM, cellular hemoglobin concentration mean; RDW, red cell distribution width; HDW, hemoglobin distribution width; WBC, white blood cell; PLT, platelet; MPV, mean platelet volume; PCT, procalcitonin; PDW platelet distribution width; INR, international normalized ratio; aPTT, activated partial thromboplastin time; ALP, alkaline phosphatase; AspAT, aspartate aminotransferase; AlAT, alanine aminotransferase; GGT, gamma-glutamyltranspeptidase; LDH, lactate dehydrogenase; IgG, immunoglobulin G; IgA, immunoglobulin A; IgM, immunoglobulin M; CRP, C-reactive protein; CK, creatine kinase; CK-MB, creatine kinase MB, cardiac marker; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglyceride; HBA1C, glycohemoglobin; NTproBNP, B-type natriuretic peptide; TSH, thyroid-stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; IL-6, interleukin 6.