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. 2022 Jan 9;14(1):2013594. doi: 10.1080/19420862.2021.2013594

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Timeline of development and production of the ZMapp antibody cocktail for emergency use and clinical trials for treating Ebola virus disease during the outbreak of 2014.⁷ Timeline representing development of the ZMapp antibody therapeutic. In December 2013 mAbs were identified, January 2014 small scale production initiated, February through March 2014 non-human primate studies performed, August 2014 GMP production initiated for emergency use of ZMapp, September 2014 a contract for ZMapp development initiated, October through December 2014 the first and second GMP production cycles completed, and February 2015 Phase I/II clinical trials begin.