Aβ |
Amyloid beta |
AD |
Alzheimer’s disease |
APOE-ε4
|
Apolipoprotein E ε4 |
APP |
Amyloid precursor protein |
BACE1 |
β-secretase |
BBB |
Blood–brain barrier |
BECN1 |
Beclin 1 |
CCL |
C–C motif chemokine ligand |
cGAS |
Cyclic guanosine monophosphate-adenosine monophosphate synthase |
ChAc |
Choline acetyltransferase |
CNS |
Central nervous system |
CRMP |
Collapsin response-mediated protein |
CXCL |
Chemokine (C–X–C motif) ligand |
DAI |
DNA-dependent activator of IFN-regulatory factor |
DAMPs |
Damage-associated molecular patterns |
DCs |
Dendritic cells |
DRG |
Dorsal root ganglia |
ds |
Double-stranded |
FGFs |
Fibroblast growth factors |
g |
Glycoprotein |
GAD |
Glutamine acid decarboxylase |
GFAP |
Glial fibrillary acidic protein |
GRP78 |
Glucose-regulated protein 78 |
GSK-3β |
Glycogen synthase kinase 3beta |
HN |
Human neural |
HNE |
4-hydroxy trans-2-nonenal |
HSE |
Herpes simplex encephalitis |
HSV-1 |
Herpes simplex virus type 1 |
HVEM |
Herpes virus entry mediator |
ICP0 |
Infection cell protein 0 |
IE |
Immediate early |
IFI16 |
IFN-γ-inducible protein 16 |
IFNs |
Interferons |
ILK |
Integrin-linked kinase |
IRF |
Interferon regulatory factor |
iNOS |
Inducible nitric oxide synthase |
IP-10 |
IFN-γ-inducible protein 10 |
ISGs |
IFN-stimulated genes |
LATs |
Latency-associated transcripts |
MAPs |
Microtubule-associated proteins |
MAVS |
Mitochondrial antiviral-signaling protein |
MDA5 |
Melanoma differentiation-associated protein 5 |
miRNAs |
MicroRNAs |
MMP |
Matrix metalloprotease |
MVs |
Microvesicles |
NF-κB |
Nuclear factor kappa B |
NFTs |
Neurofibrillary tangles |
NK |
Natural killer |
OBCs |
Organotypic brain culture slices |
OPCs |
Oligodendrocyte progenitor cells |
PAMPs |
Pathogen-associated molecular patterns |
PKA |
Protein kinase A |
PKR |
Protein kinase R |
PRRs |
Pattern recognition receptors |
PSD-95 |
Postsynaptic density protein 95 |
PUFA |
Polyunsaturated fatty acid |
RCS |
Reactive carbonyl species |
RIG-I |
Retinoic acid-inducible gene I |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen species |
sAβ |
Soluble Aβ |
snoRNAs |
Small nucleolar RNAs |
SOCS |
Suppressor of cytokine signaling |
STING |
Stimulator of interferon gene |
TG |
Trigeminal ganglion |
TH |
Tyrosine hydroxylase |
TLR |
Toll-like receptor |
TNFα |
Tumor necrosis factor α |
vhs |
Virion host shutoff |
8-OHA |
8-hydroxyadenine |
8-OHG |
8-hydroxyguanine |