Table 3.

Top ranged C5 Gene ontology gene set collection for human from gene set enrichment analysis (GSEA) comparing normal (n = 14) versus CIN3/AIS (n = 13) lesions. ES (enrichment scores), NES (normalized enrichment scores), Nom p-value (nominal p-value), FDR (false discovery rate) are included.

Rank	Gene Set	Size	ES	NES	Nom p-Value	FDR (%)
1	GO—organelle fission	12	0.88	2.27	0	0
2	GO—regulation of mitotic cell cycle	29	0.69	2.26	0	0
3	GO—mitotic cell cycle	36	0.66	2.25	0	0
4	GO—cell cycle process	42	0.62	2.19	0	0.03
5	GO—positive regulation of cell cycle	19	0.73	2.16	0	0.13
6	GO—regulation of cell cycle process	28	0.67	2.14	0	0.15
7	GO—cell cycle phase transition	24	0.68	2.13	0	0.15
8	GO—cell division	16	0.76	2.12	0	0.17
9	GO—chromosome	28	0.63	2.05	0	0.38
10	GO—chromosome organization	24	0.65	2.02	0	0.63
11	GO—cell cycle arrest	17	0.71	2.02	0	0.59
12	GO—cytoskeletal part	22	0.66	1.98	0	0.92
13	GO—regulation of cell cycle	51	0.54	1.97	0	0.93
14	GO—microtubule cytoskeleton	14	0.74	1.96	0	1.02
15	GO—cell cycle	56	0.52	1.95	0	1.11
16	GO—negative regulation of mitotic cell cycle	17	0.69	1.94	0	1.21
17	GO—negative regulation of DNA binding transcription factor activity	14	0.69	1.91	0	1.68
18	GO—microtubule organizing center	10	0.76	1.87	0	2.74
19	GO—negative regulation of transferase activity	12	0.71	1.86	0.01	2.89
20	GO—negative regulation of cell cycle process	13	0.69	1.85	0	2.97
21	GO—negative regulation of cell cycle phase transition	10	0.75	1.82	0	3.93