Table 2.

Summary of prognostic biomarkers for acute peripheral facial palsy (Metabolic parameter).

Author (Year)	Study Design	Sample Size	Age (years)	Biomarkers	Results/Conclusions
Baklacı et al. (2020) [19]	Retrospective	76 patients, 60 controls	39.76 ± 9.02, 39.31 ± 8.16 (Mean)	LDH	Mean LDH concentrations and NLR were significantly high in BP group than in control group
KARAGÖZ et al. (2020) [39]	Prospective	86 patients, 28 controls	41, 38 (Mean)	IR, HOMA-IR	The patients with higher HOMA-IR values had more severe facial dysfunction at the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value. Recovery time was significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia
Jung et al. (2018) [40]	Retrospective	124 patients	52.16 ± 14.17 (Mean)	TG, HDL-C	The recovery rate of BP was significantly lower in the MetS group than in the Non-MetS group, particularly affected by high TG
Wasano et al. (2016) [32]	Retrospective	468 patients (BP 374, RHS 94)	Mean BP 51.7 ± 14.18.8 (recovered), 57.6 ± 16.6 (unrecovered) Mean RHS 50.8 ± 18.7 (recovered), 50.5 ± 18.0 (unrecovered)	HbA1c	In the BP group, neutrophil rate, lymphocyte rate, NLR of recovered patients were significantly different than those of unrecovered patients. In RHS group monocyte rate, platelet count, MCV of recovered patients were significantly different than those of unrecovered patients
Riga et al. (2012) [41]	Prospective	56 patients	54 ± 31.7 (Mean)	HbA1c	The 20 patients with abnormal HbA1c values were more frequently diagnosed with BP of grade V/VI. However, their HBS were not found to be worse at the 6-month follow-up visit
Kanazawa et al. (2007) [42]	Prospective	76 patients	64.6 ± 8.5 (Diabetic group), 61.3 ± 8.5 (Nondiabetic group) (Mean)	HbA1c	Facial movement in the DG was poorer than that in the NDG at 3 months and 6 months after onset. In terms of the recovery rate, the rate in the DG was much lower than that in the NDG at 6 months after onset