Table 2.

Bacteria determined as potential producers or consumers of some uremic retention solutes using analysis of KEGG modules with the MetaCyc database. Bacteria presented have more than five toxin-producing reactions (without decomposing the same toxin) or more than four toxin-decomposing reactions (without synthesizing the same toxin). A complete list is available in Supplementary Table S3. Bacteria identified as both synthesizing and decomposing are presented in bold.

KEGG + MetaCyc
Synthesis (of More Than Five Toxins)	Decomposition (of More Than Four Toxins)
Oxalobacter formigenes Stenotrophomonas sp. Campylobacter coli Brevundimonas sp. Campylobacter upsaliensis Geobacter sp. Escherichia sp. Rhizobium sp. Desulfovibrio sp. Methylobacterium sp. Dialister pneumosintes Helicobacter pylori Desulfovibrio piger Edwardsiella tarda Morganella morganii Gordonibacter pamelaeae Clostridium sp. Eggerthella lenta Coprococcus catus Pediococcus acidilactici Lactobacillus fermentum Corynebacterium ammoniagenes Desulfitobacterium hafniense Paenisporosarcina sp. Paenibacillus sp. Christensenella minuta Aeromonas veronii Propionibacterium sp. Helicobacter bilis Phascolarctobacterium faecium Lachnospiraceae bacterium Helicobacter cinaedi	Escherichia sp. Rhizobium sp. Pediococcus acidilactici Lactobacillus ruminis Stenotrophomonas sp. Lactobacillus fermentum Lactobacillus paracasei Lactobacillus casei Lactobacillus rhamnosus Flavobacteriaceae bacterium Klebsiella sp. Lactobacillus amylolyticus Corynebacterium ammoniagenes Clostridium sporogenes Sphingomonas sp. Hafnia alvei Escherichia coli Providencia alcalifaciens Providencia rustigianii Enterobacter cloacae Listeria grayi Kocuria sp. Lactobacillus acidophilus Pseudomonas sp. Klebsiella oxytoca Lactobacillus helveticus