Table 1.
Identified proteins with expression significantly altered in the cerebellum of rats of the IHg group versus control group.
| a Accession ID | Protein Name Description | PLGS Score | Fold Change |
|---|---|---|---|
| P34926 | Microtubule-associated protein 1A | 71.4 | 4.35 |
| P10888 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | 146.14 | 1.46 |
| P0DP29 | Calmodulin-1 | 1825.33 | 1.39 |
| P0DP30 | Calmodulin-2 | 1825.33 | 1.39 |
| P0DP31 | Calmodulin-3 | 1867.79 | 1.38 |
| Q63345 | Myelin-oligodendrocyte glycoprotein | 290.08 | 1.30 |
| P21707 | Synaptotagmin-1 | 113.9 | 1.20 |
| P07825 | Synaptophysin | 286.54 | 1.16 |
| P68035 | Actin, alpha cardiac muscle 1 | 10,468.68 | −0.94 |
| P39052 | Dynamin-2 | 127.72 | −0.92 |
| P63039 | 60 kDa heat shock protein, mitochondrial | 870.92 | −0.91 |
| P08413 | Calcium/calmodulin-dependent protein kinase type II subunit beta | 450.44 | −0.90 |
| P11730 | Calcium/calmodulin-dependent protein kinase type II subunit gamma | 323.39 | −0.90 |
| P00406 | Cytochrome c oxidase subunit 2 | 786.54 | −0.89 |
| P0DMW0 | Heat shock 70 kDa protein 1A | 485.48 | −0.87 |
| Q06647 | ATP synthase subunit O, mitochondrial | 905.81 | −0.86 |
| P11275 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 220.44 | −0.85 |
| P12075 | Cytochrome c oxidase subunit 5B, mitochondrial | 942.79 | −0.84 |
| P15791 | Calcium/calmodulin-dependent protein kinase type II subunit delta | 215.3 | −0.84 |
| P60711 | Actin, cytoplasmic 1 | 18,625.63 | −0.83 |
| P35704 | Peroxiredoxin-2 | 2627.63 | −0.82 |
| P09951 | Synapsin-1 | 1081.01 | −0.82 |
| P02688 | Myelin basic protein | 13,414.88 | −0.76 |
| P82995 | Heat shock protein HSP 90-alpha | 1727.77 | −0.73 |
| P07895 | Superoxide dismutase [Mn], mitochondrial | 514.65 | −0.70 |
| Q5U300 | Ubiquitin-like modifier-activating enzyme 1 | 207.98 | −0.69 |
| P21575 | Dynamin-1 | 876.32 | −0.69 |
| Q08877 | Dynamin-3 | 202.61 | −0.69 |
| P31399 | ATP synthase subunit d, mitochondrial | 589.98 | −0.66 |
| P10719 | ATP synthase subunit beta, mitochondrial | 11,814.81 | −0.65 |
| O35244 | Peroxiredoxin-6 | 2447.06 | −0.64 |
| P31016 | Disks large homolog 4 | 86.82 | - |
| Q62671 | E3 ubiquitin-protein ligase UBR5 | 48.7 | - |
| O88600 | Heat shock 70 kDa protein 4 | 62.06 | - |
| Q66HA8 | Heat shock protein 105 kDa | 45.92 | - |
| Q63560 | Microtubule-associated protein 6 | 72.62 | - |
| P07722 | Myelin-associated glycoprotein | 55.31 | - |
| P34064 | Proteasome subunit alpha type-5 | 83.39 | - |
| P61959 | Small ubiquitin-related modifier 2 | 152.37 | - |
| Q5XIF4 | Small ubiquitin-related modifier 3 | 152.37 | - |
| B2RYG6 | Ubiquitin thioesterase OTUB1 | 121.2 | - |
| Q7M767 | Ubiquitin-conjugating enzyme E2 variant 2 | 735.2 | - |
+372 proteins with different status of regulation. a Accession ID according to Uniport.org database. Positive and negative values of fold change indicate up- and down-regulated proteins, respectively. Sign of—indicates exclusive expression in the control group, i.e., absent in the IHg group. Results of the comparison between the IHg group versus the control group.