Table 1.

Signature proteins for amyloid deposits. The Boruta feature selection method was applied to estimate the capacity of specific proteins to differentiate between Congo Red-positive and negative samples determined by the calculated “mean importance score “. The quantitative readout from the proteomic analysis (number of peptide spectrum matches for each protein) of the 153 biopsies divided into a training set (70% of the biopsies randomly chosen among CR+ and CR− samples) and a test set (30% of the biopsies randomly chosen among CR+ and CR− samples).

Rank	#Accession	Protein Name	Mean Importance
1	P10909	Clusterin	10.94
2	P02743	Serum amyloid P-component	10.47
3	P06727	Apolipoprotein A-IV	9.99
4	P04004	Vitronectin	9.20
5	P02649	Apolipoprotein E	8.94
6	P02748	Complement component C9	7.25
7	P12109	Collagen alpha-1(VI) chain	6.25
8	P12110	Collagen alpha-2(VI) chain	5.19
9	P12111	Collagen alpha-3(VI) chain	4.93
10	P23142	Fibulin-1	4.83