Table 1.
SAOS400.
| Quercetin (μM) | IR (Gy) | Effect § | C.I. * |
|---|---|---|---|
| SAOS400 | |||
| 25 | 5 | 0.461 | 0.75 |
| 50 | 5 | 0.628 | 0.69 |
| HT500 | |||
| 25 | 5 | 0.4 | 0.91 |
| 50 | 5 | 0.63 | 0.85 |
| SAOS400 | |||
| ABT-263 (μM) | IR (Gy) | Effect | C.I. * |
| 0.5 | 5 | 0.24 | 0.71 |
| 1.0 | 5 | 0.51 | 0.50 |
| HT500 | |||
| 0.5 | 5 | 0.39 | 0.36 |
| 1.0 | 5 | 0.42 | 0.37 |
Calculation of the combination index in irradiated SAOS400 and HT500 cells in the presence of quercetin and ABT-263. * C.I. for the combination treatment groups were generated using the equations reported by Chou and Talalay [43] using the CompuSyn software based on fraction affected (§: f.a.; “Effect” in Table 1) obtained with different doses of IR and molecules at a not-constant ratio, as described.