Table 1.
Genes | APP | BACE1 | PSEN1 | PSEN2 | MAPT | |
---|---|---|---|---|---|---|
Survival | ||||||
CA1 sector | ||||||
2 days | ↓ | ↑↑ | ↑ | ↑↑ | ↑↑ | |
7 days | ↑ | ↑ | ↑ | ↑ | ↑ | |
30 days | ↑ | ↓ | ↓ | ↓ | ↓ | |
CA3 sector | ||||||
2 days | ↓ | ↑ | ||||
7 days | ↑ | ↓ | ↑ | ↓ | ↑ | |
30 days | ↑ | ↑ | ↑ |
Expression: ↑ increase; ↑↑ increase; ↓ decrease; oscillation around control values. Genes: APP—amyloid protein precursor; BACE1—β-secretase; PSEN1—presenilin 1; PSEN2—presenilin 2; MAPT—tau protein.