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. 2021 Dec 31;23(1):437. doi: 10.3390/ijms23010437

Figure 5.

Figure 5

EMPA increases cardiac mitochondrial content in vivo. Mice were subjected to PCAL and then treated with vehicle (0.5% w/v hydroxyethyl cellulose) or EMPA (10 mg/kg/day) for 14 d followed by tissue harvest. (A) Cardiac lysates from WT mice were analyzed by Western blot analysis and quantification of mitochondrial markers COX IV, Mfn2, Opa 1, TOM 40 and OXPHOS (n = 7); (B) cardiac lysates from PKO mice were analyzed by Western blot analysis and quantification of mitochondrial markers COX IV, Mfn2, TOM 40 and OXPHOS (n ≥ 5).