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. 2022 Jan 5;23(1):577. doi: 10.3390/ijms23010577

Figure 4.

Figure 4

Analyses of the protein of TLR3 (A), MDA5 (B), and p-IRF3 (C), the mRNA of the il-6 (D) and il1-il1β (E) expressions, and the (F) mitochondria DNA copy number per cell in the WT and HSP60Tg mice livers following HFD or CD for 26 weeks. Data calculated from five to eight samples per group are expressed as the mean ± SE. * p < 0.05, ** p < 0.01 and *** p < 0.001 between the indicated groups. WT, wild-type mice; HFD, high-fat diet; HSP60Tg, mice harboring overexpression of heat shock protein 60; CD, chow diet; TLR3, toll-like receptor 3; MDA5, melanoma differentiation-associated gene 5; p-IRF3, phosphorylated-interferon regulatory factor 3; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.