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(A) Immunofluorescence analysis of mt-dsRNA in HepG2 cells after treatment with pUSE-amp vector containing HSP60 for 24 h. The mt-dsRNA levels are significantly lower in containing the HSP60-transfected vector in vitro. (B) Data are expressed as the mean ± SE of the six to seven samples per group. *** indicates a p < 0.001 (C) Tom20 is the mitochondrial outer membrane protein. Confocal image study confirmed that HSP60 restricts the release of mt-dsRNA (green) in vitro.
