Table 1.
Comparison of the changes in the four groups.
| WT-CD | WT-HFD | HSP60Tg-CD | HSP60Tg-HFD | |
|---|---|---|---|---|
| Body weight (g) | 35.01 ± 0.65 | 46.74 ± 1.04 a | 30.26 ± 0.67 a | 33.87 ± 0.97 bc |
| GPT (dU/L) | 20.6 ± 6.1 | 58.1 ± 7.1 a | 16.7 ± 4.2 | 28.8 ± 7.1 c |
| Triglycerides (mg/dL) | 99 ± 16.2 | 155.3 ± 18.4 a | 125.7 ± 17.7 | 127.6 ± 20.3 |
| Total Cholesterol (mg/dL) | 183.3 ± 7.5 | 202.9 ± 7.5 a | 189.4 ± 2.4 | 197.8 ± 7.0 |
| Subcutaneous fat (g) | 1.09 ± 0.12 | 3.6 ± 0.34 a | 0.69 ± 0.09 | 1.24 ± 0.37 c |
| Visceral fat (g) | 1.11 ± 0.10 | 1.85 ± 0.12 a | 0.56 ± 0.09 a | 1.14 ± 0.2 bc |
| Mesenteric (g) | 0.47 ± 0.06 | 0.86 ± 0.07 a | 0.14 ± 0.04 a | 0.24 ± 0.07 c |
| Liver (g) | 1.65 ± 0.06 | 2.14 ± 0.17 a | 1.5 ± 0.08 | 1.55 ± 0.03 c |
| Pancreas (g) | 0.3 ± 0.02 | 0.25 ± 0.03 | 0.23 ± 0.02 a | 0.24 ± 0.02 |
| Spleen (g) | 0.09 ± 0.01 | 0.11 ± 0.02 | 0.09 ± 0.03 | 0.13 ± 0.02 |
| Kidney (g) | 0.55 ± 0.04 | 0.64 ± 0.04 | 0.48 ± 0.03 | 0.49 ± 0.02 c |
Data obtained from 4–8 samples and expressed as the mean ± standard error. a p < 0.05 versus WT-CD. b p < 0.05 versus HSP60Tg-CD. c p < 0.05 versus WT-HFD. CD: chow diet; HFD: high-fat diet; HSP60: heat shock protein 60; Tg: transgenic; WT: wild type.