| UPS | Ubiquitin proteasome system |
| DUBs | Deubiquitinases |
| RIG-I | Retinoic acid-inducible gene-I |
| RLR | RIG-I-like receptors |
| GMP | Guanosine monophosphate |
| AMP | Adenine monophosphate |
| cGAS | cyclic-GMP-AMP synthase |
| IFN | Interferon |
| HSV | Herpes simplex virus |
| VZV | Varicella zoster virus |
| HCMV | Human cytomegalovirus |
| HHV | Human herpesvirus |
| EBV | Epstein-Barr virus |
| KSHV | Kaposi’s sarcoma-associated herpesvirus |
| PRRs | Pathogen recognition receptors |
| PAMPs | Pathogen-associated molecular patterns |
| TLRs | Toll-like receptors |
| NOD | Nucleotide-binding oligomerization domain |
| NLR | NOD-like receptors |
| Ub | Ubiquitin |
| E6-AP | E6-associated protein |
| HECT | Homologous to E6-associated protein (E6-AP) carboxyl terminus |
| RBR | RING-between-RING |
| CRLs | Cullin-RING ligases |
| APC/C | Anaphase-promoting complex/cyclosome |
| Nedd4 | Neuronal precursor cell-expressed developmentally downregulated 4 |
| HERC | HECT and RCC1-like domain |
| RCC1 | Regulators of chromosome condensation 1 |
| RLDs | RCC-1-like domains |
| USPs | Ubiquitin-specific proteases |
| OTUs | Ovarian tumor |
| UCHs | Ubiquitin C-terminal hydrolases |
| MJDs | Machado-Joseph disease |
| MIU | Motif interacting with ubiquitin |
| MINDYs | MIU-containing novel DUB |
| JAMM | JAB1/MPN/MOV34 metalloenzyme family |
| AMSH | Associated Molecule with the SH3-domain of STAM |
| UBA | Ubiquitin associated |
| UIM | Ubiquitin interacting motif |
| ZnF | Zinc finger |
| JOSD | Josephin domain |
| ZUFSP | Zinc finger with UFM1-specific peptidase domain protein |
| HUBL | HAUSP ubiquitin-like domain |
| HAUSP | Herpesvirus-associated ubiquitin-specific protease |
| RNA | Ribonucleic acid |
| MDA | Melanoma differentiation-associated |
| LGP | Laboratory of genetics and physiology |
| CARD | Caspase activation recruitment domains |
| dsRNA | Double strand RNA |
| MAVS | Mitochondrial antiviral signaling |
| TNF | Tumor necrotic factor |
| TRAF | TNF Receptor Associated Factor |
| TANK | TRAF Family Member Associated NF-kB Activator |
| TBK1 | TANK-binding kinase |
| IKK | I-kappa B kinase |
| IRF | Interferon regulatory factor |
| TRIM | Tripartite motif |
| PCBP | Poly(C)-binding protein |
| VSV | Vesicular Stomatitis Virus |
| HOIP | HOIL-1L interacting protein |
| HOIL-1L | Heme-oxidized IRP2 ubiquitin ligase-1 |
| LUBAC | Linear ubiquitin assembly complex |
| CYLD | Cylindromatosis tumor suppressor |
| OTUD | OTU domain |
| ISG | Interferon stimulating genes |
| CHIP | Carboxy-terminus of Hsc70-interacting protein |
| LMP | Latent membrane protein |
| MHC | Major histocompatibility complex |
| ORF61 | Open reading frame61 |
| IFI16 | Interferon-Inducible Protein 16 |
| ER | Endoplasmic recticulum |
| AMFR | Autocrine motility factor receptor |
| INSIG1 | Insulin-induced gene 1 |
| MUL1 | Mitochondrial E3 Ubiquitin Ligase 1 |
| NF-kB | Nuclear Factor Kappa B |
| PEL | Primary effusion lymphoma |
| DAMPs | Damage-associated molecular pattern |
| NLRP1 | NLR-family pyrin domain (PYD)-containing 1 |
| AIM2 | Absent In Melanoma 2 |
| ACS | Apoptosis-associated speck-like protein containing a CARD domain |
| Cbl | Casitas B-cell lymphoma |
| BRCA1 | Breast cancer 1 |
| BRCC3 | BRCA1-BRCA2-containing complex |
| BRISC | BRCC36 isopeptidase complex |
| ABRO1 | Abraxas brother protein 1 |
| RIPK3 | Receptor-interacting serine/threonine-protein kinase 3 |