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qPCR analysis of SMC-specific markers in the aortic tissue of Hspg2−/−-Tg mice without AD at 10- and 20-weeks of age. RNA expression of SMC-specific marker genes, Acta2 and Myh11, was significantly decreased in Hspg2−/−-Tg mice. Myocardin (Myocd) expression in Hspg2−/−-Tg mice was not significantly different from that in WT-Tg mice. RNA expression levels were normalized to that of β-actin and are indicated relative to the latter. (Mean ± SEM, n = 5, * p < 0.05 vs. WT-Tg).
