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. 2021 Dec 28;23(1):315. doi: 10.3390/ijms23010315

Figure 6.

Figure 6

Expression and activity of matrix metalloproteinase (MMPs). (A) RNA expression of matrix metalloproteinase in Hspg2−/−-Tg mice without AD showed no significant difference compared to that in WT-Tg mice. RNA expression levels were normalized to that of β-actin and are indicated as relative to the latter. (Mean ± SEM, 10 w; n = 6, 20 w; n = 3) (B) In gelatin zymography, MMP-2 activity did not differ, and MMP-9 activity was not detected in the aorta of WT-Tg and Hspg2−/−-Tg mice without AD. MMP2 activity is indicated relative to pro-MMP2 activity. (Mean ± SEM, n = 3).