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. Author manuscript; available in PMC: 2022 Jan 10.
Published in final edited form as: Cogn Behav Neurol. 2014 Jun;27(2):107–116. doi: 10.1097/WNN.0000000000000028

Figure 1.

Figure 1.

Representative fragments following restriction enzyme digestions for genotyping rs6311 and rs6314. A. Following digestion with HpaII, rs6311 heterozygous samples were represented by two peaks (top panel), while homozygous SNP allele “A” subjects (middle panel) or ancestral allele “G” subjects (bottom panel) were represented by single peaks at 143bp and 108bp, respectively. Still apparent in the middle panel, but not interfering with genotype calls is residual undigested full-length 151bp amplicons. B. Digestion of amplicons containing rs6314 with BsmI resulted in the same pattern where homozygous ancestral “C” allele subjects (bottom panel) or SNP “T” allele subjects (top panel) resulted in single peaks of 85bp and 157bp, respectively, and heterozygous samples having both peaks (middle panel).