Table 2.

Cytokines which exhibited increased intensity ratios in both soft culture conditions (> 1), where at least one ratio was significantly increased (i.e., significantly increased expression on soft compared to stiff substrates).

	Soft : Stiff		Soft-to-Stiff (1) : Stiff-to-Stiff (1)
Cytokine	Intensity Ratio	p value	Intensity Ratio	p value
Endocan	1.7 ± 0.5	0.0124*	1.5 ± 0.3	0.0994
IGFBP-6	2.7 ± 1.6	0.0148*	1.5 ± 0.6	0.8053
MCP-1	1.7 ± 0.2	0.0597	2.2 ± 0.7	0.0090**

Data are shown as mean ± standard deviation.

^*p < 0.05.

^**p < 0.01.

(IGFBP-6 = Insulin-like growth factor-binding protein-6, MCP-1 = Monocyte chemoattractant protein-1).