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. 2021 Dec 27;11(1):139. doi: 10.3390/jcm11010139

Table 2.

Causes of CPAP titration, primary and secondary failures.

Causes of CPAP Failure Titration Failure
N = 10 out of 400
Primary Failure
N = 78 out of 307
Secondary Failure
N = 64 out of 229
CPAP titration pressure not effective 5 (3 M) NA NA
Predominant central apnoea 1 M NA NA
CPAP was not tolerated 4 (3 M) 15 (9 M) 31 (23 M)
CPAP was too expensive NA 24 (19 M) NA
Preferred other treatment * NA 18 (16 M) 11 (10 M)
Afraid of CPAP treatment - 4 (2 M) -
Treatment of comorbidities was more important NA 3 (1 M) -
Did not feel benefit - - 2 (1 M)
Spontaneous improvement NA NA 8 (7 M)
Other reasons or declined to answer NA 14 (10 M) 12 M
Total N 10 (7 M) 78 (57 M) 64 (53 M)

* Other treatment: weight reduction (diet, bariatric surgery, palate surgery), positional treatment (i.e., avoiding sleep in supine position). CPAP—continuous positive airway pressure, NA—not applicable, M—males, N—number.