Figure 5.

Treatment with kMSC results in lower CD25 expression on T cells, but not reduced numbers of T_reg. Three weeks after transplant, mice were immunophenotyped. (a) Percentage of CD4⁺ and CD8⁺ cells in peripheral blood at 3 weeks after transplant. (b) Percentage of CD4⁺CD25⁺ and CD8⁺CD25⁺ cells in peripheral blood at 3 weeks after transplant. (c) Representative dot plot of labelled CD4⁺CD25⁺FoxP3⁺ cells from spleens of transplanted mice, 3 weeks after transplant. (d) Graphical representation of the percentage of CD4⁺CD25⁺FoxP3⁺ cells from spleens of transplanted mice. Each dot from the graphs represents data from one mouse. Error bars are means ± SEM, * p < 0.05.