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. 2021 Dec 23;23(1):146. doi: 10.3390/ijms23010146

Figure 7.

Figure 7

Invadopodia beneath the nucleus of an MDA-MB-231 breast cancer cell in a type I collagen matrix are both proteolytic and adhesive. MMP-14 is immunostained in green, active integrin β1 in magenta, and F-actin in red. The nucleus is counterstained in blue with Hoechst 33,342 dye. Scale bar: 5 µm.