Comparison 8. Antidepressants: Global assessment.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Comparing nr (%) of successfully treated patients with IBS	11	750	Risk Ratio (M‐H, Random, 95% CI)	1.57 [1.23, 2.00]
1.1 SSRI's	4	227	Risk Ratio (M‐H, Random, 95% CI)	1.79 [1.01, 3.20]
1.2 TCA's	8	523	Risk Ratio (M‐H, Random, 95% CI)	1.45 [1.13, 1.86]
2 Comparing scores on global assessment in patients with IBS	1	22	Std. Mean Difference (IV, Random, 95% CI)	3.32 [1.95, 4.68]
2.1 SSRI's	1	22	Std. Mean Difference (IV, Random, 95% CI)	3.32 [1.95, 4.68]
2.2 TCA's	0	0	Std. Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]