Comparison 9. Antidepressants: Outcome on symptom score.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Comparing nr (%) of successfully treated IBS patients	3	159	Risk Ratio (M‐H, Fixed, 95% CI)	1.99 [1.32, 2.99]
1.1 SSRI's	1	72	Risk Ratio (M‐H, Fixed, 95% CI)	1.36 [0.81, 2.27]
1.2 TCA's	2	87	Risk Ratio (M‐H, Fixed, 95% CI)	3.16 [1.59, 6.29]
2 Comparing symptom scores of IBS patients	2	122	Std. Mean Difference (IV, Random, 95% CI)	0.38 [‐0.30, 1.06]
2.1 SSRI's	1	72	Std. Mean Difference (IV, Random, 95% CI)	0.05 [‐0.41, 0.52]
2.2 TCA's	1	50	Std. Mean Difference (IV, Random, 95% CI)	0.75 [0.17, 1.32]