Bergmann 1991.

Methods	RCT
Participants	35 patients Secondary care Clinical diagnosis and investigations
Interventions	Antidepressant 3 months Trimipramine 50 mg OD
Outcomes	Global assessment, dichotomous
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Double‐blind, methods not described
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not described
Selective reporting (reporting bias)	Low risk	Expected outcomes reported
Other bias	Low risk	The study appears to be free of other sources of bias